Sri Lanka captain Angelo Mathews won the toss and elected to bat against South Africa in the first one-day international in Dambulla on Sunday.
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The hosts, upbeat after a 2-0 whitewash of the Proteas in the Test series, included two fast bowlers and two spinners in their starting eleven.
"We have the (2019) World Cup at the back of the mind for sure, so we'll try a few combinations," Mathews, who last played an ODI in January, said at the toss.
"We're good to go and I'm looking forward to it."
Proteas skipper Faf du Plessis said South Africa's disappointing show in the Tests will not affect their chances in the five ODIs.
"The Tests shouldn't affect our game. A young squad, (a) lot of energy, and that excites me. Even if they make mistakes, it's about getting better and learning from them," said du Plessis.
